Ceftriaxone Injection IP

Product Description

🉠Ceftriaxone Injection IP

🔠What It Is:

Ceftriaxone is a third-generation cephalosporin antibiotic with a broad spectrum of activity against many Gram-positive and Gram-negative bacteria. It is widely used to treat serious bacterial infections.

🔠Composition:

• Each vial contains:

  • Ceftriaxone Sodium equivalent to 1 g or 250 mg or 500 mg (depending on vial size)

• Usually supplied as a sterile powder for reconstitution.

… Indications:

• Respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

• Meningitis

• Gonorrhea and other sexually transmitted infections

• Intra-abdominal infections

• Septicemia and bacteremia

• Surgical prophylaxis

🉠Dosage & Administration:

• Adults:

  • Typical dose: 1“2 g IV or IM once daily

  • Maximum dose: 4 g/day (divided doses if necessary)

• Children:

  • 50“75 mg/kg/day (max 2 g/day) in one or two divided doses

• Route:

  • Intravenous (IV) infusion or Intramuscular (IM) injection

  • IM injection should be given deep into a large muscle mass (e.g., gluteal)

• Reconstitution:

  • With sterile water or suitable diluent for injection

  • For IV: Dilute in 10“40 mL of compatible IV fluids (e.g., 0.9% NS or 5% Dextrose) and infuse over 30 minutes

  • For IM: Reconstitute with 1% lidocaine (without epinephrine) for pain relief

šï Contraindications:

• Hypersensitivity to cephalosporins or penicillins

• Neonates with hyperbilirubinemia or prematurity (risk of bilirubin displacement)

• Concurrent calcium-containing IV solutions in neonates (<28 days)

šï Precautions:

• Use with caution in patients with renal or hepatic impairment

• Monitor for signs of superinfection

• Prolonged use may lead to fungal or bacterial overgrowth

• Avoid mixing with calcium-containing solutions in neonates (risk of precipitates)

🪠Side Effects:

🊠Storage:

• Store powder at room temperature (20“25C)

• Protect from moisture

• Use reconstituted solution immediately or store refrigerated (2“8C) for up to 24 hours

📝 Summary Table: