Rabeprazole Gastrol Resistand and Domeperidone Prolonged Release Capsules

About Rabeprazole Gastrol Resistand and Domeperidone Prolonged Release Capsules

EC = Enteric-Coated
SR = Sustained Release

… Uses / Indications:

• Gastroesophageal reflux disease (GERD)

• Functional dyspepsia

• Acid reflux / heartburn

• Gastritis

• Nausea and bloating related to delayed gastric emptying

• Non-ulcer dyspepsia

🊠Dosage & Administration:

🊠Swallow whole with water “ do not chew or crush
 Take at the same time each day for best results

šï Precautions:

• Use with caution in:

  • Patients with cardiac arrhythmias or QT prolongation

  • Those on antifungals, macrolide antibiotics, or SSRIs (possible drug interactions)

• Long-term PPI use may lead to:

  • Vitamin B12 deficiency

  • Hypomagnesemia

  • Increased fracture risk

• Not recommended in:

  • Moderate to severe hepatic impairment (Domperidone)

  • Children under 12 years (unless specified by a doctor)

🪠Possible Side Effects:

🔄 Drug Interactions:

• Domperidone:

  • Avoid with ketoconazole, erythromycin, fluconazole “ increases QT risk

  • QT-prolonging drugs should be avoided

• Rabeprazole:

  • May reduce absorption of iron, calcium, Vitamin B12, and certain antifungals (e.g., itraconazole)

  • Caution with warfarin, digoxin, and clopidogrel

🊠Storage:

• Store at room temperature (15“25C)

• Protect from heat, moisture, and direct sunlight

• Keep out of reach of children