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Febuxostat is a medication used to lower uric acid levels in the blood. It is primarily prescribed for gout and hyperuricemia to prevent gout attacks and complications.
Ingredient | Strength |
---|---|
Febuxostat | 40 mg |
Chronic gout
Hyperuricemia (high uric acid levels)
Prevention of uric acid nephropathy
Management of tophi in gout patients
Typical starting dose: 40 mg once daily
Dose may be increased to 80 mg daily based on serum uric acid levels and physician advice
Take with or without food
Maintain adequate hydration to prevent kidney stones
Monitor serum uric acid regularly during treatment
Use with caution in patients with liver or kidney impairment
Not recommended during pregnancy and lactation unless necessary
Monitor for cardiovascular risk factors (history of heart disease)
Avoid use in patients with severe renal impairment unless advised by physician
May increase risk of hypersensitivity reactions
Common Side Effects | Serious / Rare Side Effects |
---|---|
Nausea, diarrhea | Liver function abnormalities |
Rash | Severe hypersensitivity reactions |
Gout flare (early treatment) | Cardiovascular events (rare) |
Headache, dizziness | Stevens-Johnson syndrome (very rare) |
Azathioprine or mercaptopurine: avoid concomitant use due to toxicity risk
Theophylline: may increase levelsmonitor
Drugs metabolized by liver enzymes (CYP1A2, CYP2C8) may interact
Store at room temperature below 25C
Protect from moisture and light
Keep out of reach of children
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