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A non-steroidal anti-inflammatory drug (NSAID) combination used for rapid relief from pain, inflammation, and fever. It includes:
Nimesulide a selective COX-2 inhibitor with anti-inflammatory and analgesic effects
Paracetamol (Acetaminophen) a widely used antipyretic and mild analgesic
Together, they provide synergistic action for acute pain relief and fever control.
Ingredient | Typical Strength | Function |
---|---|---|
Nimesulide | 100 mg | Reduces pain and inflammation (COX-2 inhibitor) |
Paracetamol | 325 mg or 500 mg | Reduces fever and mild-to-moderate pain |
Formulations may vary slightly by brand. Some brands use Paracetamol 500mg for stronger antipyretic effect.
Fever associated with inflammation
Headache, toothache, earache
Musculoskeletal pain, sprains, and strains
Backache, joint pain, arthritic pain
Post-operative or post-traumatic pain
Dysmenorrhea (painful menstruation)
Not recommended for long-term use or chronic pain conditions due to hepatotoxicity risk.
Patient Type | Recommended Dose |
---|---|
Adults | 1 tablet twice daily, after meals |
Children (<12 yrs) | Not recommended unless specifically prescribed |
Elderly | Use with caution; may need dose adjustment |
ð Take with food or milk to reduce gastric side effects
ð Minimum 8-hour interval between doses
Avoid alcohol increases risk of liver toxicity
Not recommended in:
Liver disease
Peptic ulcer or GI bleeding
Kidney impairment
Pregnancy (especially 3rd trimester) and breastfeeding
Monitor liver enzymes during prolonged use
Not for use in viral infections in children (Nimesulide is banned for pediatric use in several countries)
Common | Less Common / Serious |
---|---|
Nausea, vomiting, indigestion | Liver toxicity (with prolonged or overdose) |
Drowsiness, fatigue | Skin rash or allergic reaction |
Gastric discomfort, heartburn | GI bleeding (rare) |
Stop immediately and consult a doctor if yellowing of skin/eyes, severe abdominal pain, or rash occurs.
Store at room temperature (<25C)
Keep away from heat, moisture, and direct sunlight
Keep out of reach of children
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