Methylprednisolone is a synthetic corticosteroid (glucocorticoid) used to reduce inflammation, immune response, and treat a wide range of allergic, autoimmune, and inflammatory disorders.
Composition (per tablet):
| Ingredient |
Strength |
Function |
| Methylprednisolone IP |
4 mg |
Corticosteroid anti-inflammatory & immunosuppressive |
Uses / Indications:
Methylprednisolone 4 mg tablets are commonly prescribed for:
-
Rheumatoid arthritis, osteoarthritis
-
Asthma, COPD exacerbations
-
Allergic reactions (severe)
-
Autoimmune diseases (e.g., lupus, psoriasis)
-
Skin conditions (eczema, dermatitis)
-
Inflammatory bowel diseases (ulcerative colitis, Crohn's)
-
Neurological conditions (e.g., multiple sclerosis relapse)
-
Organ transplant rejection prevention
Dosage & Administration:
| Typical Dose |
Varies Based On |
| 448 mg/day (in divided doses or once daily) |
Severity of condition, patient weight, response |
Always follow physician's guidance corticosteroid dosing is highly individualized.
Taper slowlydo not stop abruptly after long-term use to avoid adrenal suppression.
When & How to Take:
Precautions & Warnings:
-
Use with caution in:
-
Hypertension
-
Diabetes mellitus
-
Osteoporosis
-
Peptic ulcers
-
Psychiatric conditions
-
Long-term use may lead to:
-
Cushings syndrome
-
Adrenal suppression
-
Bone loss / fractures
-
Increased infection risk
-
Pregnancy & lactation: Use only if prescribed
-
Pediatric use: May affect growth in children
Possible Side Effects:
| Common |
Serious / Rare |
| Weight gain, fluid retention |
Mood swings, depression, psychosis |
| Indigestion, increased appetite |
Cataracts, glaucoma |
| Insomnia, nervousness |
High blood sugar or blood pressure |
| Acne, delayed wound healing |
Adrenal crisis if stopped abruptly |
Drug Interactions:
-
May interact with:
-
NSAIDs ( GI ulcer risk)
-
Diuretics ( potassium loss)
-
Insulin/antidiabetics ( effectiveness)
-
Vaccines ( vaccine efficacy)
Storage:
-
Store at room temperature (1525C)
-
Keep in a dry place, away from direct sunlight
-
Keep out of reach of children