Pregabalin & Nortriptyline Hydrochloride Tablets

About Pregabalin & Nortriptyline Hydrochloride Tablets

Pregabalin & Nortriptyline Hydrochloride Tablets

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What It Is:

A combination medication used to treat neuropathic pain and associated symptoms. It contains:

• Pregabalin a GABA analogue that reduces abnormal nerve signaling

• Nortriptyline Hydrochloride a tricyclic antidepressant (TCA) that enhances pain modulation and improves mood

This combo works synergistically to relieve chronic nerve pain and improve patient quality of life.

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Typical Composition (per tablet):

Ingredient	Common Strengths	Function
Pregabalin	75 mg / 150 mg	Reduces nerve signal overactivity and pain
Nortriptyline HCl	10 mg / 20 mg	Enhances serotonin & norepinephrine; reduces pain perception

Strengths may vary by brand or patient condition.

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Uses / Indications:

• Peripheral Neuropathy (Diabetic, Alcoholic, Chemotherapy-induced)

• Postherpetic Neuralgia

• Fibromyalgia

• Chronic Neuropathic Pain

• Lumbar/Cervical Spondylosis with nerve involvement

• Mood-related symptoms with chronic pain

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Dosage & Administration:

Formulation	Typical Dose
Pregabalin 75 mg + Nortriptyline 10 mg	Once or twice daily after meals
Pregabalin 150 mg + Nortriptyline 1020 mg	Usually once daily at bedtime

Take at a fixed time each day, preferably in the evening if it causes drowsiness.
Swallow whole with water; do not chew or crush.

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i Precautions:

• May cause drowsiness, dizziness, or blurred vision

• Avoid alcohol it increases sedation and risk of CNS depression

• Use cautiously in:

  • Renal impairment

  • Cardiac disorders (due to Nortriptyline)

  • Elderly patients

  • Pregnancy & breastfeeding only if prescribed

• Do not discontinue abruptly risk of withdrawal symptoms

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a Possible Side Effects:

Common	Less Common / Serious
Drowsiness, dizziness	Irregular heartbeat (rare)
Dry mouth, constipation	Mood changes, confusion
Increased appetite, weight gain	Suicidal thoughts (rare, with TCAs)
Blurred vision	Urinary retention (rare)

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Storage:

• Store below 25C, in a dry place

• Protect from light and moisture

• Keep out of reach of children

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Summary Table:

Aspect	Details
Form	Oral Tablet
Use	Neuropathic pain with or without mood symptoms
Typical Strengths	Pregabalin 75150 mg + Nortriptyline 1020 mg
Dosage	Once or twice daily (as prescribed)
Side Effects	Drowsiness, dry mouth, constipation
Special Caution	Cardiac patients, CNS effects, taper if stopping

Effective Nerve Pain Relief

This medication is formulated specifically for neuropathic pain and chronic pain management, targeting discomfort associated with nerve damage or conditions such as fibromyalgia. By combining Pregabalin and Nortriptyline, it addresses both pain signaling and neurotransmitter imbalances, offering reliable, targeted relief for individuals suffering from persistent nerve pain.


Convenient Prescription Tablets

Packaged in practical strips, these oral tablets are easy to take, ensuring proper adherence to your treatment regimen. The 10x10 box format supports straightforward dose tracking and storage, while prescription-only access ensures safe use under medical supervision. Always take the tablets as directed by your doctor for best results.


Usage and Storage Guidelines

For safety and optimal effectiveness, take the tablets after meals or as prescribed. Store them in a cool, dry environment, protected from direct sunlight. Follow your healthcare provider's dosage recommendations and complete the full course to maximize therapeutic benefits and reduce nerve pain symptoms.