Hydroxyzine Hydrochloride Tablets Ip 25 mg

Ingredient	Strength	Function
Hydroxyzine Hydrochloride	25 mg	Antihistamine; sedative; anxiolytic

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Uses / Indications:

• Allergic conditions: Urticaria, dermatitis, allergic rhinitis, pruritus

• Anxiety and tension: Short-term management of anxiety disorders

• Sedation: Preoperative or pre-procedural sedation

• Sleep disorders (mild insomnia)

• Nausea and vomiting (especially when related to motion sickness)

• Adjunct in opioid-induced pruritus

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Dosage & Administration:

Indication	Typical Adult Dose
Allergy / Pruritus	25 mg 23 times daily
Anxiety	50100 mg/day in divided doses
Sedation	50100 mg as a single dose at bedtime
Children	Use under medical supervision only

• Take with or without food

• Swallow whole with water

• Avoid operating machinery or driving after taking the tablet

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Precautions:

• CNS depression: May cause drowsiness, dizziness

• Elderly patients: Increased risk of sedation and confusion

• Avoid alcohol and other CNS depressants

• Not recommended in pregnancy (especially 1st trimester) unless clearly needed

• Use with caution in renal or hepatic impairment

• May prolong QT interval in susceptible individuals

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Possible Side Effects:

Common Side Effects	Serious / Rare Side Effects
Drowsiness, dry mouth	QT prolongation, arrhythmias (rare)
Dizziness, blurred vision	Confusion or hallucinations (high doses)
Headache, constipation	Allergic reactions (rash, swelling)
Fatigue, nausea	Seizures (extremely rare)

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Drug Interactions:

• Increased sedation with:

  • Alcohol

  • Benzodiazepines

  • Opioids

  • Antipsychotics

• May interact with drugs that prolong the QT interval (e.g. erythromycin, some antifungals)

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Storage:

• Store below 25C

• Protect from light and moisture

• Keep away from children

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