Pantoprazole Gastro Resistand and Domperidone Prolonged Release Capsules IP

About Pantoprazole Gastro Resistand and Domperidone Prolonged Release Capsules IP

A combination medication containing:

• Rabeprazole Sodium (Enteric Coated) ï a proton pump inhibitor (PPI) that reduces stomach acid secretion, helping heal and prevent acid-related gastrointestinal disorders.

• Domperidone (Sustained Release) ï a prokinetic agent that promotes gastric emptying and helps relieve nausea and vomiting.

This combination is commonly used to manage acid reflux, GERD, dyspepsia, and gastric motility disorders.

ï Typical Composition (per capsule):

ï Uses / Indications:

• Gastroesophageal reflux disease (GERD)

• Peptic ulcers

• Functional dyspepsia

• Gastritis and acid-related stomach disorders

• Nausea and vomiting associated with delayed gastric emptying

• Prevention of nausea caused by acid-lowering therapy

ï Dosage & Administration:

Swallow whole; do not crush or chew.
Take consistently at the same time each day.

ïï Precautions:

• Use cautiously in patients with:

  • Liver impairment

  • Prolonged QT interval or cardiac arrhythmias (due to Domperidone)

  • Electrolyte imbalances

• Avoid use in children below 12 years (dose adjustments may be necessary)

• Inform physician about any other medications, especially those affecting heart rhythm

ï Possible Side Effects:

🔄 Drug Interactions:

• Rabeprazole may reduce absorption of drugs requiring acidic environment (e.g., ketoconazole)

• Domperidone risk increased with QT-prolonging drugs (e.g., some antibiotics, antipsychotics)

• Avoid concurrent use with other prokinetics without medical advice

ï Storage:

• Store at room temperature below 25C

• Keep capsules in original packaging to protect from moisture

• Keep out of reach of children