About Metformin Hydrochloride SR & Glimepiride Tablets IP
Metformin Hydrochloride SR & Glimepiride Tablets IP is a combination of two oral antihyperglycemic agents used in the management of type 2 diabetes mellitus, particularly when diet, exercise, and monotherapy with a single agent do not result in adequate glycemic control.
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Metformin Hydrochloride (Sustained Release) belongs to the biguanide class of antidiabetic drugs. It acts primarily by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. The sustained-release formulation allows for prolonged drug action and improved gastrointestinal tolerability.
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Glimepiride is a second-generation sulfonylurea that stimulates insulin release from functioning pancreatic beta cells. It also exhibits extrapancreatic activity, including enhanced insulin sensitivity at peripheral target sites.
This fixed-dose combination provides a complementary mechanism of action to effectively lower blood glucose levels, reduce insulin resistance, and improve beta-cell responsiveness. It is intended for use as an adjunct to diet and exercise in patients with type 2 diabetes mellitus.
Dual Action Control for Type 2 DiabetesThis combination of Metformin SR and Glimepiride is formulated to provide comprehensive glucose control. Metformin primarily lowers hepatic glucose production, while Glimepiride promotes pancreatic insulin release, offering synergistic benefits when taken as directed. The sustained release form helps ensure stable medication levels in your system.
Convenient and Safe DosageEach tablet is designed for once-daily oral administration, generally with your first main meal, as advised by your doctor. Packaged for stability in blister packs, the tablets should be stored below 30C, protected from light and moisture, to preserve efficacy throughout their 24-month shelf life.
FAQs of Metformin Hydrochloride SR & Glimepiride Tablets IP:
Q: How should I take Metformin Hydrochloride SR & Glimepiride Tablets?
A: The tablets are meant to be swallowed whole with water, typically once a day with your first main meal or as your physician prescribes. Do not crush or chew sustained release tablets, and always follow your doctors specific instructions for optimal glycemic control.
Q: What are the benefits of combining Metformin SR and Glimepiride in one tablet?
A: Combining these two medications leverages their complementary mechanisms: Metformin improves insulin sensitivity and Glimepiride stimulates insulin production. Together, they offer better blood glucose management for adults with type 2 diabetes than either medication alone.
Q: When can I expect to start seeing results from this medication?
A: Blood glucose control improvements may be noted within a few days to weeks, but full benefits often become evident after consistent, regular use for several weeks as prescribed. Always monitor your blood sugar as instructed by your healthcare provider.
Q: Where should I store the tablets to maintain their effectiveness?
A: Keep the tablets in their original blister pack, stored in a cool, dry, and dark location below 30C, away from moisture and direct sunlight. Proper storage helps maintain the medications potency and shelf life.
Q: What precautions should I be aware of while using this medication?
A: This medication should only be used under medical supervision. Common side effects include hypoglycemia, gastrointestinal discomfort, and dizziness. Inform your doctor of any unusual symptoms, especially severe low blood sugar episodes.
Q: Is this medication suitable for everyone with type 2 diabetes?
A: Metformin Hydrochloride SR & Glimepiride Tablets are recommended for adults with type 2 diabetes, but dosing and suitability must be assessed by a healthcare professional. It is not suitable for children or pregnant women unless specifically prescribed by a doctor.
Q: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember with food. If its almost time for your next dose, skip the missed tablet and continue your regular schedule. Do not take a double dose to make up for a missed one.