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This is a dual-action gastrointestinal therapy combining:
Pantoprazole a proton pump inhibitor (PPI) that reduces excess stomach acid
Domperidone a prokinetic agent that enhances gastric motility and prevents nausea
It is used primarily to treat acid reflux, GERD, functional dyspepsia, and associated nausea or bloating.
Ingredient | Strength | Function |
---|---|---|
Pantoprazole Sodium (enteric-coated) | 40 mg | Reduces gastric acid secretion (PPI) |
Domperidone (sustained release) | 30 mg | Enhances gut motility, anti-nausea agent |
Also available in Pantoprazole 20 mg + Domperidone 30 mg SR formulations
Gastroesophageal reflux disease (GERD)
Functional dyspepsia
Heartburn and acid peptic disorders
Nausea and bloating due to gastric stasis
Peptic ulcers
Prevention of NSAID-induced gastritis
Typical Adult Dose | 1 capsule once daily, preferably before breakfast |
---|---|
Mode of Intake | Swallow whole; do not chew or crush |
Duration | Usually 48 weeks, or as advised by physician |
For best efficacy, take 3060 minutes before meals
Not recommended for long-term use without medical supervision
Caution in elderly patients and those with:
QT prolongation or cardiac arrhythmia risk
Hepatic or renal impairment
Monitor magnesium, calcium, B12 levels in long-term PPI use
Rule out gastric malignancy before long-term acid suppression
Common | Less Common / Serious |
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Headache, flatulence, diarrhea | Hypomagnesemia (with prolonged use) |
Abdominal discomfort, nausea | B12 deficiency (long-term PPI use) |
Drowsiness, dry mouth (Domperidone) | QT prolongation, arrhythmias (rare, Domperidone) |
Mild rash or dizziness | Liver enzyme elevation (rare) |
Ketoconazole, itraconazole absorption reduced due to acid suppression
Warfarin, phenytoin, digoxin may require monitoring
Levodopa Domperidone may antagonize its effects
Avoid co-use with macrolides, azole antifungals, or antipsychotics (risk of QT prolongation)
Store below 25C in a dry place
Keep away from direct sunlight and moisture
Keep out of reach of children
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