Mefenamic Acid and Paracetamol Suspension

Product Description

Mefenamic Acid and Paracetamol Suspension is a combination pediatric syrup or oral suspension commonly prescribed for the management of fever and mild to moderate pain in children.

🔠Composition and Action:

1. Mefenamic Acid

   • Class: Non-Steroidal Anti-Inflammatory Drug (NSAID)

   • Action: Reduces inflammation, pain, and fever by inhibiting prostaglandin synthesis.

   • Used For: Pain relief, particularly in inflammatory conditions like toothaches, earaches, musculoskeletal pain.

2. Paracetamol (Acetaminophen)

   • Class: Analgesic and Antipyretic

   • Action: Reduces fever and relieves pain by acting on the hypothalamic heat-regulating center and inhibiting prostaglandin synthesis in the CNS.

   • Used For: Fever, headaches, mild to moderate pain.

… Indications:

• Fever of various origins (viral or bacterial)

• Headache

• Toothache

• Earache

• Muscle pain

• Post-vaccination fever

• Mild to moderate inflammatory pain

🊠Typical Dosage (for children):

• Dosage is usually based on weight and prescribed by a pediatrician.

• For example:

  • Mefenamic Acid: 4“6 mg/kg/dose every 8 hours

  • Paracetamol: 10“15 mg/kg/dose every 4“6 hours

• Important: Never exceed the maximum daily dose of Paracetamol (usually 60 mg/kg/day in children).

šï Precautions:

• Use with caution in children under 6 months.

• Avoid in children with peptic ulcers, kidney issues, or known NSAID allergy.

• Prolonged use can lead to gastritis, liver toxicity (from Paracetamol), or kidney issues.

• Should not be combined with other NSAIDs or Paracetamol-containing products to avoid overdose.

🪠Side Effects:

• Abdominal pain

• Nausea or vomiting

• Allergic reactions (rash, itching)

• Dizziness

• Rarely: liver or kidney dysfunction (in overdose or long-term use)