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Itraconazole 100 mg is a systemic antifungal medication from the triazole class, used to treat a broad range of fungal infections. It works by inhibiting ergosterol synthesis, an essential component of fungal cell membranes, leading to fungal cell death.
Generic Name: Itraconazole
Strength: 100 mg
Form: Capsule
Pharmacopoeia Standard: British Pharmacopoeia (BP)
Dosage Form: Hard gelatin capsule
Route: Oral (by mouth)
Itraconazole 100 mg is used to treat:
Dermatophytosis (Tinea corporis, cruris, pedis)
Pityriasis versicolor
Onychomycosis (fungal infection of nails)
Vaginal candidiasis
Oropharyngeal and esophageal candidiasis
Systemic fungal infections like:
Histoplasmosis
Blastomycosis
Aspergillosis
| Condition | Dose | Duration |
|---|---|---|
| Tinea corporis/cruris | 100 mg once daily | 15 days |
| Tinea pedis | 100 mg twice daily | 7 days |
| Pityriasis versicolor | 100 mg once daily | 715 days |
| Onychomycosis (fingernails) | 100 mg twice daily | 6 weeks |
| Onychomycosis (toenails) | 100 mg twice daily | 12 weeks |
| Systemic infections | 200400 mg per day (in divided doses) | As per doctor's advice |
Take with food, preferably a fatty meal, to improve absorption.
Do not crush, chew, or open the capsule.
Common:
Nausea or vomiting
Abdominal pain
Headache
Rash
Diarrhea
Taste disturbances
Rare but serious:
Liver damage (watch for yellow eyes/skin, dark urine)
Heart failure symptoms (swelling, shortness of breath)
Severe allergic reactions
Do NOT use in:
Patients with congestive heart failure (CHF)
Pregnant women (unless life-threatening infection)
Use with caution in:
Liver or kidney disease
Elderly patients
ð Drug interactions:
Itraconazole interacts with many medications, including:
Statins (simvastatin, lovastatin)
Rifampicin (reduces efficacy)
Warfarin
Antacids (reduce absorption avoid taking within 2 hours)
Store at room temperature (below 25C)
Protect from light and moisture
Keep out of reach of children
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Itraconazole 100 (Cipla, Intas, Mankind, etc.)
Itromed 100
Itrotab 100
Itrazole 100
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