Pantoprazole for Injection

Product Description

🉠Pantoprazole for Injection

🔠What It Is:

Pantoprazole is a proton pump inhibitor (PPI) used to reduce gastric acid secretion. The injectable form is used when oral administration is not possible, especially in acute care or hospital settings.

🔠Composition:

• Each vial contains:

  • Pantoprazole Sodium Sesquihydrate equivalent to 40 mg Pantoprazole

• Form: Lyophilized powder for reconstitution

… Indications / Uses:

Used in the treatment of:

• Gastroesophageal reflux disease (GERD) with erosive esophagitis

• Zollinger-Ellison Syndrome and other hypersecretory conditions

• Stress ulcers in critically ill patients

• Peptic ulcer disease

• Prevention of aspiration pneumonia (in surgical/ICU patients)

• Acid suppression before endoscopy for upper GI bleeding

🉠Dosage & Administration:

To be administered by healthcare professionals only

• Usual Adult Dose:

  • 40 mg once daily via IV injection or IV infusion

📌 Reconstitution Instructions:

1. For IV Injection (Bolus):

   • Reconstitute vial with 10 mL of 0.9% Normal Saline

   • Inject slowly over at least 2 minutes

2. For IV Infusion:

   • Reconstitute and dilute in 100 mL of 0.9% Normal Saline or 5% Dextrose

   • Infuse over 15 minutes

šï Do not use other diluents like Ringer™s or Sodium Bicarbonate

📆 Duration of Therapy:

• Typically 7 days or until oral therapy can be resumed

• Long-term use may be required in Zollinger-Ellison Syndrome

šï Contraindications:

• Known hypersensitivity to Pantoprazole or other PPIs

• Caution in hepatic impairment

• Not recommended for pediatric use via injection unless prescribed

🪠Side Effects:

šï Important Notes:

• IV Pantoprazole is bioequivalent to oral formulation, but used only when oral route is not feasible

• Do not mix with other drugs in the same syringe or IV line

• Switch to oral Pantoprazole 40 mg once the patient can tolerate oral intake

🊠Storage:

• Store vials at 15“25C

• Protect from light and moisture

• Use reconstituted solution immediately, or within 4 hours if refrigerated