TELMISARTAN, AMLODIPINE TABLETS IP

Product Description

Telmisartan, Amlodipine Tablets IP are a combination medication used to treat high blood pressure (hypertension). Here's a detailed overview:

📌 Composition

Each tablet typically contains:

• Telmisartan ï an angiotensin II receptor blocker (ARB)

• Amlodipine ï a calcium channel blocker (CCB)

Common strengths:

• Telmisartan 40 mg + Amlodipine 5 mg

• Telmisartan 80 mg + Amlodipine 5 mg

• Telmisartan 40 mg + Amlodipine 10 mg

• Telmisartan 80 mg + Amlodipine 10 mg

(IP = Indian Pharmacopoeia standard)

ï Uses

• Management of hypertension

• Helps reduce risk of heart attacks, strokes, and kidney problems in hypertensive patients

• May be used when monotherapy (single drug treatment) is not sufficient

ïïï Mechanism of Action

• Telmisartan: Blocks angiotensin II receptors ï causes vasodilation, reduces aldosterone, and lowers blood pressure.

• Amlodipine: Inhibits calcium influx into vascular smooth muscles ï causes arterial relaxation, reduces vascular resistance, and lowers blood pressure.

ïï Side Effects

Common:

• Dizziness

• Swelling in ankles or feet (edema)

• Headache

• Fatigue

• Flushing

Serious (rare):

• Hypotension (very low BP)

• Hyperkalemia (high potassium levels)

• Kidney impairment

• Allergic reactions

📌 Contraindications

• Known hypersensitivity to either drug

• Severe liver or kidney disease (use with caution)

• Pregnancy (especially 2nd and 3rd trimester ï Telmisartan is contraindicated)

ï Important Notes

• Take the medicine at the same time daily, with or without food.

• Donït stop suddenly unless directed by your doctor.

• Avoid potassium supplements or salt substitutes unless advised.

• Monitor blood pressure, kidney function, and electrolytes regularly.