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Duchenne Muscular Dystrophy (DMD) a major approved indication
Rheumatoid arthritis, lupus, polymyositis
Severe allergies & skin conditions (eczema, psoriasis)
Nephrotic syndrome
Asthma, bronchitis, COPD exacerbations
Inflammatory bowel disease (Crohns, ulcerative colitis)
Post-transplant immunosuppression
Autoimmune hematological disorders (e.g., ITP)
Condition | Typical Dose |
---|---|
General inflammation | 618 mg once daily |
DMD (Duchenne) | 0.9 mg/kg/day |
Autoimmune conditions | Individualized based on response |
ð Always take after food to reduce stomach upset
Morning dose preferred to mimic natural cortisol rhythm
ï Do not stop suddenly taper gradually as per physician's advice
Use with caution in:
Diabetes or pre-diabetes
Hypertension
Osteoporosis
Peptic ulcers
Infections (latent or active TB, fungal infections)
May suppress immune response avoid live vaccines
Long-term use in children may affect growth
Common | Serious / Long-term |
---|---|
Weight gain, increased appetite | Osteoporosis, cataracts, glaucoma |
Mood changes, insomnia | Growth suppression in children |
Indigestion, bloating | Adrenal suppression |
Acne, fluid retention | Increased infection risk |
Can interact with:
Antidiabetic drugs ( effectiveness)
NSAIDs ( GI bleeding risk)
Antifungals, anticonvulsants (alter metabolism)
Vaccines ( efficacy; avoid live vaccines)
Store below 25C
Keep in a dry place away from sunlight
Keep out of reach of children
Price: