RIFAXIMIN & METRONIDAZOLE TABLETS

About RIFAXIMIN & METRONIDAZOLE TABLETS

• Rifaximin  200 mg or sometimes 400 mg

  
  

  Metronidazole  200 mg 400 mg or 500 mg

  
  

  Exact dosages may vary by brand and prescription

  
  

   Uses

  This combination is used in the treatment of

  
  

  Intestinal infections eg travelers diarrhea infectious diarrhea

  
  

  Amoebiasis

  
  

  Giardiasis

  
  

  Small intestinal bacterial overgrowth SIBO

  
  

  Clostridium difficileassociated diarrhea in some cases

  
  

  Colitis

  
  

  Liverrelated encephalopathy Rifaximin component

  
  

   Mechanism of Action

  Rifaximin A poorly absorbed antibiotic that acts locally in the gut targeting a wide range of grampositive and gramnegative bacteria by inhibiting RNA synthesis

  
  

  Metronidazole A nitroimidazole antibiotic effective against anaerobic bacteria and protozoa by disrupting DNA synthesis

  
  

   Dosage Typical

  Commonly prescribed as 1 tablet two to three times daily for 510 days depending on the infection

  
  

  Must be taken after food to minimize stomach upset

  
  

  Always follow a doctors prescription

  
  

   Side Effects

  Metallic taste in mouth Metronidazole

  
  

  Nausea or vomiting

  
  

  Abdominal cramps

  
  

  Headache or dizziness

  
  

  Darkcolored urine Metronidazole  harmless

  
  

  Allergic reactions rare

  
  

  Longterm metronidazole use risk of neuropathy

  
  

   Precautions

  Avoid alcohol during and for 48 hours after Metronidazole treatment can cause severe reactions

  
  

  Not recommended in pregnancy or breastfeeding unless prescribed

  
  

  Use cautiously in patients with liver disease

  
  

  Avoid prolonged use without medical advice